Thursday, April 23, 2015

Part 2: Chapters 10-19 Question 16

In retrospect, what was the “pepper” that Tom had seen under the light microscope?

2 comments:

  1. The “pepper” that Tom seen under the light microscope “were really inclusion bodies” (Preston 119). Before this, Tom noticed that a group of cells that transformed into something that looked like chocolate chip cookies were actually cells covered in block of pure viruses known as inclusion bodies. They grow inside the cell, and bricks appear at the center. They move outward, towards the cell’s surface, and once the brick touches the inner surface of the cell wall, it breaks apart. The virus is thread shaped and tries to push out the cell wall in order to break free. During the course of this, the cell wall grows outward, causing it to change shape. When the virus has successfully broke free from the cell, it then goes to the bloodstream of the host and multiplies, taking more cells and forming more bricks. Bases on this finding, Tom then realized that the cells he looked at in the flask ten days ago had specks of inclusion bodies. He saw that these cells were also swollen and fat and it was because they were filled with bricks of viruses. These cells were at the brink of bursting, just like how the other cells were. It was like a continuing cycle. If these cells were to come in contact with other cells, they would also get infected as well.

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  2. Inclusion bodies have been described as “like thousands of black carbonated worms packed tightly” (Medler 85). Inclusion bodies are basically clumps of intracellular material that are associated with a virus. The inclusion bodies found in the monkey culture was pertaining to Ebola Zaire. Out of all the filoviruses, Ebola Zaire is the most deadly causes 9 out of 10 of those infected to die. Ebola Zaire inclusion bodies are “extraordinarily large and vivid” (Murphy). Since these were Ebola inclusion bodies, they would not only multiple at a high speed but also cause massive damage to the cells that it would take over.

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