Thursday, April 23, 2015

Part 2: Chapters 10-19 Question 12

How did Thomas Geisbert determine that the cells under his microscope were a form of
Ebola?

2 comments:

  1. Thomas Geisbert found out that the cells under the microscope were a type of Ebola because the cells had several of the same characteristics and symptoms. The cells were completely obliterated and ripped to shreds. The cells contained lots of material that greatly resembled Ebola. The internal material was lengthy and looked like many worms and rope all jumbled up inside the cells. Viruses that closely mimic the same structure as rope are evidently filoviruses. Marburg is a type of filovirus, a thread virus. The viruses in the cells had to be some sort of Ebola strain. It looked exactly like what had killed Peter Cardinal. Geisbert feared for his life, since he handled the deadly virus with little consideration or safety procedures. The images of the cells and viruses proved to be in fact Ebola. They looked like snakes all tangled up in complicated knots. The cells were deformed and filled with lots of viruses, growing and multiplying hundreds of times. The cells had exploded due to the pressure that was building up inside over many days. Ebola uses cells as factories to produce and keep producing virus “babies” until the cells can no longer continue holding all of the offspring inside. All of these sign and characteristics made Geisbert confident and sure that the viruses in the cells were Ebola (Preston, 1994, pg.148-150).

    Preston, R. (1994). The Hot Zone. New York: Random House.

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  2. In continuation to what Kimberley stated, Jahrling saw the Geisbert’s microscope results and knew that they both handled the virus so Jahrling went ahead and tested for Marburg and Ebola. Jahrling tested some of the monkey cell culture with blood from victims with Marburg, Ebola Zaire and Ebola Sudan. This was the only way to identify which virus was in the monkeys because the cells would glow when they interacted with the correct virus. After testing the sample twice due to the belief of there being a contamination, Jahrling was able to identify that the monkey sample that he and Geisbert handled had Ebola Zaire.

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